References on Cardiovascular Research using ALZET^® Osmotic Pumps

Animal models of human cardiovascular disease such as those for spontaneously hypertensive rats (SHR) or balloon injury have long represented an important area of research and discovery. Whether studying hypertension, restenosis, nitric oxide (NO) and NO synthase inhibitors, or the renin-angiotensin system, the use of ALZET osmotic pumps to deliver agents continuously provides a powerful tool for experimentation. ALZET pumps have been used to deliver antihypertensive drugs, angiogenic agents, compounds which inhibit vascular restenosis, and hormones with cardiovascular effects. The following reference lists contain examples of these types of research:

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Aldosterone

Angiotensin II

Antihypertensives

Antisense Oligonucleotides

Epinephrine

Growth Factors

Immunosuppressants

Intravenous Infusion

Nitric Oxide Research

Norepinephrine

Vasopressin

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