Neuroscience Research Using ALZET^® Osmotic Pumps

By direct intracerebral infusion, ALZET pumps allow researchers to bypass the blood-brain barrier. These pumps can also be used for continuous systemic infusion or targeted delivery to specific sites, such as the spinal cord or peripheral nerves. A variety of agents which have CNS activity have been delivered in this manner, including drugs of abuse, neurotrophic factors, neurotransmitters, and receptor antagonists. Examples of this research are included in the reference lists below:

Some of these bibliographies may be large and take a short while to display. These bibliographies are updated frequently. As the references are listed most recent first, you may wish to truncate your printing to ten pages or less.

 

Amphetamines

Antibodies

Anticonvulsive Agents

Antidepressants

Antipsychotics

Antisense Oligonucleotides

Cannabinoids

Cerebral Ischemia (stroke)

Cocaine

Cytokines

Delayed CNS Delivery

Dopamine

Dopaminergics

GABA

Growth Factors

Intracerebroventricular Administration (Rats)

Intracerebroventricular Administration (Mice)

Intracerebroventricular Administration (all animals)

Intrathecal Infusion

Naloxone & Naltrexone

Neurodegenerative Diseases

Neurotrophic Factors

Opioids and Opiate Peptides

Opioid Receptor Research

Peptide Delivery to the CNS

Solid Tissue Microperfusion

Spinal Cord Injury Research

Targeted Delivery to Peripheral Nerves

Tolerance and Dependence

The following information relevant to neuroscience research can be ordered from the ALZET Technical Services page:

• Intracranial Peptide Delivery Review by White and Schwartz
• Review on CNS Infusion Methods by T. Hagg
• A newsletter which features information on 'Targeted Delivery to Peripheral Nerves'
• Models of Neurodegenerative Disease
• Mouse CNS Research
  

If you are interested in a specific agent and did not find it listed above, check the index by Agent Administered.