“However, the s.c. mini-osmotic pump delivery of recombinant leptin raised circulating leptin into the physiological range (Table 2). These data confirmed the effectiveness of the s.c. infusion of leptin at 0.1 mg/day in restoring serum leptin levels.” Zhang et al. Journal of Endocrinology 2002; 174:455-461.

News

ALZET Promotions

Below is a list of previous ALZET promotions and names for the corresponding winners. Congratulations to the lucky winners, and thank you to all scientists who participated in these special ALZET promotions:

Bibliography Update 2007: The winner of the iPod nano is Karine Lux from the Jackson Laboratory - Sacramento

SFN 2007: The winner of the iPod touch is Melissa Ferguson from University of Florida - Gainesville

Neuroscience Newsletter Mailing 2007: The winner of the Apple iPod nano is Andrea Neely from University of North Carolina - Chapel Hill

Bibliography Update Mailer 2007: The winner of the Apple iPod nano is Dr. Linda Gutierrez from Wilkes University.

Endocrine Society 2007: The winner of the Apple iPod nano is Dr. Gunapala Shetty from the MD Anderson Cancer Center.

Experimental Biology 2007: The winner of the Apple iPod nano is Dr. Tandra Chakraborty from Adelphi University.

AACR 2007: The winner of the Apple iPod nano is Dr. Christopher Gubish from the University of Pittsburgh. 

SOT 2007: The winner of the Apple iPod nano is Carroll Henschel from BioMarin Pharmaceutical Inc.

Product News

ALZET introduces new pump model (2006)

Available Now

Model 2006 Nominal Specifications:

  • Volume: 200 µl
  • Release rate: 0.15 µl/hour
  • Duration: 6 weeks

Key features:

  • Longest duration pump in any size, ideal for chronic studies in mice, rats, and other animal models
  • Low flow rate, ideal for tissue perfusion

 

ALZET introduces new pump model (1004)

Model 1004 Nominal Specifications:

  • Volume: 100 µl
  • Release rate: 0.11 µl/hour
  • Duration: 4 weeks

Key features:

  • Longest duration pump in 100 µl size; ideal for chronic studies in small mice and young rats
  • Slowest flow rate in ALZET product line, ideal for tissue perfusion

ALZET Osmotic Pumps Celebrate 30 Years of Continuous Delivery

Introduced in 1977, this year marks 30 years since the first ALZET Osmotic Pump was sold.  Over the last three decades the ALZET pumps have been proven as an integral research tool, allowing for the continuous delivery of test compounds. 

 

ALZET introduces three new specialized catheters.

These catheters are fully compatible with the ALZET Osmotic Pumps and are constructed from biocompatible materials. See more information on our catheter page.  The various models include the following:

    • Rat Intrathecal Catheter - Short
    • Mouse Jugular - Adjustable Length
    • Mouse Jugular - Adjustable Length/Large Tip

 

Company News

7/17/2007

DURECT Reports Positive Results from POSIDUR(TM) Phase IIb Hernia Trial, Triggering $8 million Milestone Payment from Nycomed

Read More

6/27/2007

DURECT Announces the Initiation of Sufentanil Patch Phase II Study by Endo Pharmaceuticals

Read More

1/3/2007

DURECT Starts Phase II Dosing for TRANSDUR(TM)-Bupivacaine (DUR-843)

Read More

11/29/06

DURECT and Nycomed Sign $202 Million Agreement to Develop and Commercialize POSIDUR(TM) in Europe and Other Select Countries

Read More


Archive

 

Latest Research Using ALZET Pumps

Steroid hormones act transsynaptically within the Forebrain to regulate neuronal phenotype and song stereotypy. JOURNAL OF NEUROSCIENCE 2007; 27(44):12045-12057. >>> Meitzen J, et al.

PubMed Link

Continuous administration of the three thrombospondin-1 type 1 repeats recombinant protein improves the potency of therapy in an orthotopic human pancreatic cancer model. Cancer Letters 2007; 247(1):143-149. >>> Zhang X, Connolly C, et al. "Continuous administration of 3TSR reduced dosage and improved therapeutic potency."

PubMed Link

Discovery, Synthesis, and in Vivo Activity of a New Class of Pyrazoloquinazolines as Selective Inhibitors of Aurora B Kinase. J Med Chem 2007. >>> Mortlock AA, Foote KM, Heron NM, Jung FH, Pasquet G, Lohmann JJ et al.


Evaluation of an osmotic pump for microdialysis sampling in an awake and untethered rat. J Neurosci Methods 2007; 160(2):269-275. >>> Cooper JD, Heppert KE, Davies MI, Lunte SM. "the osmotic pump can be an invaluable improvement over the syringe pump.".

PubMed Link

 

 

 

 

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