ALZET Catheters
Via
a catheter, ALZET® Osmotic Pumps can deliver substances
into the venous or arterial circulation, into the brain, or into
any organ lumen, or solid tissue. DURECT Corporation offers a
range of specialized catheters, compatible with ALZET pumps, to
enable targeted delivery to a variety of sites.
ALZET Pumps are compatible with tubing which has an I.D range of 0.58 mm-0.76 mm (0.023"-0.030").
Catheter
applications with ALZET Osmotic Pumps
- Direct delivery of test agents pecisely into any target tissue
or organ
- Delay administration of test agents to allow for a surgical
recovery period
- Infuse for a short period using a longer duration pump
- Create a time-patterned delivery of an agent
Note:
No catheter is necessary when systemic delivery is desired. This
is accomplished by subcutaneous or intraperitoneal implantation
of an ALZET pump without a catheter.
Polyethylene (PE) and
Vinyl Tubing
Medical grade PE and Vinyl tubing, the most common catheter types used
in laboratory animal research, are available sterile, individually packaged,
and ready to use.
Features
- Sterile
- Medical grade
- Pre-cut to 15 cm lengths
- Individually packaged
- Ready to use
- Fit all pump models
Tubing Specifications
Description
| Item No.
| Length
| Outside Diameter
| Inside Diameter
| Volume
|
Vinyl Tubing
(10 per bag) |
0007760 |
15cm
(6 in) |
1.14 mm
(0.045 in) |
0.69 mm
(0.027 in) |
3.739 µl/cm |
Polyethylene
(10 per bag) |
0007750 |
15cm
(6 in) |
1.22 mm
(0.048 in) |
0.76 mm
(0.030 in) |
4.566 µl/cm |
Specialized Catheters*
Rat
Jugular Catheter |
|
 |
Order No.: 0007710
Catheter Material: Silicone
Specifications:
15.24 cm (6") of silicone catheter
(0.94 OD; 0.51 mm ID) with a Dacron suture patch and ALZET connection
(1.19 mm OD; 0.61 mm ID)
Optimum Animal Size:
250+ grams (for <250 gram rats, cut
tip to size for proper placement)
Features & Benefits:
- Dacron patch facilitates anchoring to tissue
- Silicone material is very flexible and less traumatic to vessels
- Bevel tip if desired for easier insertion into vessels
- ETO sterilized
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Rat
Femoral Catheter |
|
 |
Order No.: 0007720
Catheter Material: Polyurethane (PU)
Specifications:
20.32 cm (8") of Polyurethane catheter
(1.02 mm OD; 0.61 mm ID); designed for intravenous cannulation
Optimum Animal Size:
Up to 300+ grams (for <175 gram rats,
cut tip to size for proper placement)
Features & Benefits:
- Retention beads at 3.81, 5.08, and 7.62 cm from the tip facilitate
anchoring to tissue
- Medical grade polyurethane softens at body temperature
- Fits directly to pump (no step-up needed)
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Rat
Femoral Catheter (Tapered) |
 |
Order No.: 0007730
Catheter Material: Opaque Polyurethane
Specifications:
20.32 cm (8") of tapered radio-opaque
polyurethane (1.40 mm to 0.99 mm OD; 0.61 mm constant ID); designed
for intravenous cannulation
Optimum Animal Size:
Up to 300+ grams (for <175 gram rats,
cut tip to size for proper placement)
Features & Benefits:
- Retention beads at 3.81, 5.08, and 7.62 cm from the tip facilitate
anchoring to tissue
- Medical grade, tapered polyurethane minimizes kinking
- Radio-opaque material and smooth surface minimize clotting
- Lumen maintains consistent ID, so that the catheter can be
shortened without compromising its tight fit onto pump
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Rat
Intrathecal Catheter |
|
 |
Order No.: 0007740
Catheter Material: Polyurethane (PU)
Specifications:
10 cm of 28G PU (0.36 mm OD; 0.18 mm ID)
connected to 12.7 cm PU (0.84 mm OD; 0.36 mm ID) and ALZET connection
(1.02 mm OD; 0.61 mm ID) with stainless steel stylet. Total catheter
length is 23.7 cm (9.33").
Optimum Animal Size:
Up to 300+ grams (cut distal end to desired
length for proper placement)
Features & Benefits:
- Designed for occipital approach
- Teflon coated stylet slides smoothly out of catheter
- Protected tubing junction minimizes kinking at exit point
from intrathecal space
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Rat
Intrathecal Catheter (Short) |
|
 |
Order No.: 0007741
Catheter Material: Polyurethane (PU)
Specifications:
10 cm of 28G PU (0.36 mm OD; 0.18 mm ID)
connected to 4.0 cm PU (0.84 mm OD; 0.36 mm ID) and ALZET connection
(1.02 mm OD; 0.61 mm ID) with stainless steel stylet. Total catheter
length is 15.0 cm (5.90").
Optimum Animal Size:
Up to 300+ grams (cut distal end to desired
length for proper placement)
Features & Benefits:
- Shorter length for non-occipital approach
- Teflon coated stylet slides smoothly out of catheter
- Protected tubing junction minimizes kinking at exit point
from intrathecal space
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Mouse
Jugular Catheter |
|
 |
Order No.: 0007700
Catheter Material: Polyurethane (PU)
Specifications:
13mm of 28G PU (0.36 mm OD; 0.18 mm ID)
connected to 63.5 mm PU (0.84 mm OD; 0.36 mm ID) and ALZET connection
(1.02 mm OD; 0.61 mm ID). Total catheter length is 8.8 cm (3.46").
Optimum Animal Size:
30+ grams (insertion marks for adaptation
to smaller animals)
Features & Benefits:
- Retention beads at 13 and 38 mm from the tip facilitate anchoring
to tissue
- Catheter tip optimum for use with other small vessels (e.g.,
femoral, carotid, etc.)
- Marked at 9 and 11 mm to simplify adaptation for <25 and
25-30 gram animals respectively
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Mouse
Jugular Catheter (Adjustable Length) |
 |
Order No.: 0007701
Catheter Material: Polyurethane (PU)
Specifications:
13mm of 28G PU (0.36 mm OD; 0.18 mm ID)
connected to 25.4 mm PU (0.84 mm OD; 0.36 mm ID) connected to
a 50 mm ALZET connection (1.02 mm OD; 0.61 mm ID). Total catheter
length is 8.8 cm (3.46").
Optimum Animal Size:
30+ grams (insertion marks for adaptation
to smaller animals)
Features & Benefits:
- ALZET connection can be trimmed to achieve smaller lengths
- Catheter tip optimum for use with other small vessels (e.g.,
femoral, carotid, etc.)
- Retention beads at 13 and 35 mm from the tip facilitate anchoring
to tissue
- Marked at 9 and 11 mm to simplify adaptation for <25 and
25-30 gram animals respectively
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Mouse
Jugular Catheter (Adjustable Length-Large
Tip) |
 |
Order No.: 0007702
Catheter Material: Polyurethane (PU)
Specifications:
44.5 mm of PU (0.84
mm OD; 0.36 mm ID) connected to a 50 mm ALZET connection (1.02
mm OD; 0.61 mm ID). Total catheter length is 9.5 cm (3.74").
Optimum Animal Size:
30+ grams (insertion marks for adaptation
to smaller animals)
Features & Benefits:
- ALZET connection can be trimmed to achieve smaller lengths
- Catheter tip optimum for jugular cannulation
- Retention beads at 13 and 35 mm from the tip facilitate anchoring
to tissue
- Marked at 9 and 11 mm to simplify adaptation for <25 and
25-30 gram animals respectively
|
*All
specialized catheters are supplied sterile (ETO sterilized) |
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of page
Catheter
applications with ALZET Osmotic Pumps
- Direct delivery of test agents pecisely into any target tissue
or organ
- Delay administration of test agents to allow for a surgical
recovery period
- Infuse for a short period using a longer duration pump
- Create a time-patterned delivery of an agent
Note:
No catheter is necessary when systemic delivery is desired. This
is accomplished by subcutaneous or intraperitoneal implantation
of an ALZET pump without a catheter.
Common
Routes of Administration Requiring Use of a Catheter
- Articular cavity
- Blood vessels
- Bone
- Brain (solid tissue)
- Brain (ventricles)
- Ear
- Eye
- Muscle
- Nerves
- Spinal cord
- Stomach
- Tumors