References on Using ALZET® Osmotic Pumps In Space

14223 Horn, E.R., Gabriel, M., Horn, E.R. Gender- Related Sensitivity of Development and Growth to Real Microgravity in Xenopus laevis. Journal of Experimental Zoology Part A-Ecological Genetics and Physiology 2014; 321(--):1-12. >>> Nettle powder; Water, spring; In vitro; Toad (tadpole); 2ML2; Animal info (Xenopus laevis); teratology; spaceflight;.

4610 Rasmussen, O, Gmünder, F, Tairbekov, M, Kordyum, E.L, Lozovaya, V.V, Baggerud, C, Iversen, T.-H  ESA 1990; 307(--):527-530. >>> Growth medium; In vitro (cell culture); mp used to deliver growth medium to protoplasts during spaceflight.

4382 Adams, G.R., McCue, S.A., Bodell, P.W., Zeng, M., Baldwin, K.M. Effects of spaceflight and thyroid deficiency on hindlimb development. I. Muscle mass and IGF-I expression. J. Appl. Physiol 2000; 88(--):894-903. >>> Propylthiouracil; IP; Rat (lactating); 2ML4; Teratology; Propythiouracil was delivered to neonates via dam's milk; pilot studies showed that this resulted in similar depression in plasma T3 and T4 to direct PTU injection to neonates; Propylthiouracil is an antihyperthyroid that blocks the conversion of L-thyroxine T4 to T3; spaceflight.

15651 Turner, R.T. Effects of short-term spaceflight and recombinant human growth hormone (rhGH) on bone growth in young rats. Aviation Space Environ Med 1995; 66(--):763-769. >>> Growth hormone, recomb. human; Phosphate; F68 detergent; SC; rat; controls received mp w/vehicle; peptides; spaceflight.

4240 Turner, R.T. Effects of short-term spaceflight and recombinant human growth hormone (rhGH) on bone growth in young rats. Aviation Space Environ Med 1995; 66(--):763-769. >>> Growth hormone, recomb. human; Phosphate; F68 detergent; SC; rat; controls received mp w/vehicle; peptides; spaceflight.

4513 Gmunder, F.K., Suter, R.N., Kiess, M., Urfer, R., Nordau, C.-G., Cogoli, A. Mammalian cell cultivation in space. Adv. Space Res 1989; 9(-11-):119-127. >>> Culture media; Glucose; Fetal calf serum; HEPES buffer; Gentamycin;; in vitro (cell culture); 2001; 2002; diagram of dynamic cell culture system on page 123; in vitro; spaceflight.

3709 Lorenzi, G., Gmunder, F.K., Cogoli, A. Cultivation of hamster kidney cells in a dynamic cell culture system in space (spacelab IML-1 mission). Microgravity Sci. Technol 1993; VI/1(--):34-38. >>> NaHCO3; Glucose; HEPES; DMEM; Serum, fetal calf; Gentamicin; in vitro (cell culture); 2001; mp connected to cell culture chamber;"...the osmotic pump delivered sufficient fresh medium to support cell growth in the perfusion chambers."p. 37; spaceflight.

3397 Jiang, B., Roy, R.R., Navarro, C., Edgerton, V.R. Absence of a growth hormone effect on rat soleus atrophy during a 4-day spaceflight. Am. Physiol. Soc 1993; 74(-2-):527-531. >>> Growth hormone, recomb. human; Phosphate; F-68; SC; rat; controls received mp w/ vehicle; functionality of mp verified by immunoassay; stability verified by HPLC; musculoskeletal; spaceflight.

2157 Cronin, M., Battersby, J., Hancock, W., Schwall, T., Clark, R. Delivery of recombinant human growth hormone to rats during exposure to microgravity on NASA space shuttle discovery. Physiologist 1992; 35(-1-):S51-S52. >>> Growth hormone, recomb. human; F68 detergent; Phosphate; SC; rat; functionality of mp verified upon removal by immunoassay; peptides; mp performed well in microgravity; spaceflight.

1382 Gmunder, F.K., Nordau, C.-G., Tschopp, A., Huber, B., Cogoli, A. Dynamic cell culture system: a new cell cultivation instrument for biological experiments in space. J. Biotechnol 1988; 7(--):217-228. >>> Culture media, DMEM; HEPES; Serum, fetal calf; Gentamicin; Glucose; in vitro (cell culture); 2001; Mp connected to cell culture chamber; cytotoxicity described; spaceflight.

 

Since 1977, scientist around the world have used ALZET pumps to conduct their research, publishing their results in high-impact journals. The ALZET bibliography now contains over 16,000 publications! We can perform a custom search for references relevant to your research.

Request your ALZET bibliography search!

 

Order the ALZET SurgicalImplantation Video

What researchers are saying...

“We switched to a 21-day minipumps paradigm using a dose that mimics serum antidepressant concentrations in humans because this regimen resulted in a more consistent and robust decrease in serotonin transporter levels in rats than what is observed with daily injections of serotonin reuptake inhibitors.” Weinshenker et al. 2002 Brain Research 946:239-246.