Immunology Research using ALZET® Osmotic Pumps
Efforts to understand the
immune system have necessitated that researchers develop strategies
for manipulation of the immune response under experimental conditions.
In many cases, the continuous infusion of biological and chemical
agents may be critical to mimic the natural immune response, or to
minimize toxicity from high dose administration. ALZET osmotic pumps
have proven to be of instrumental value to scientists in the field
of immunology, enabling continuous systemic or targeted delivery of
antibodies, cytokines, immunosuppressants, antigens, antivirals, or
genetic material.
Recent examples of this work are included in a general list of immunology references or in the following bibliographies:
Some of these bibliographies may be large and take a short while to display. These bibliographies are updated frequently. As the references are listed most recent first, you may wish to truncate your printing to ten pages or less.
If you are interested in a specific agent and did not find it listed above, check the index by Agent Administered.
Looking for references? We can help!
ALZET will perform a custom bibliography search for you! ALZET pumps have been used to deliver hundreds of different compounds, including proteins and peptides, in a myriad of different experimental applications. We have recently updated our database, which now contains over 11,000 references that can help you guide your research project!
Pump Advantages
- Ensure around-the-clock exposure to test agents at predictable levels
- Permit continuous administration of short half-life proteins and peptides
- Provide a convenient method for the chronic dosing of laboratory animals
- Minimize unwanted experimental variables and ensure reproducible, consistent results
- Eliminate the need for nighttime or weekend dosing
- Reduce handling and stress to laboratory animals
- Small enough for use in mice or very young rats
- Allow for targeted delivery of agents to virtually any tissue
- Cost-effective research tool