Immunology Research with ALZET® Pumps
Efforts to understand the
immune system have necessitated that researchers develop strategies
for manipulation of the immune response under experimental conditions.
In many cases, the continuous infusion of biological and chemical
agents may be critical to mimic the natural immune response, or to
minimize toxicity from high dose administration. ALZET osmotic pumps
have been instrumental to scientists in the field
of immunology, enabling continuous systemic or targeted delivery of
antibodies, cytokines, immunosuppressants, antigens, antivirals, or
Recent examples of this work are included in a general list of immunology references or in the bibliographies* listed below. If you are interested in a specific agent not listed below, check the index by Agent Administered.
*Some of these bibliographies may be large and take a short while to display. These bibliographies are updated frequently. As the references are listed most recent first, you may wish to truncate your printing to ten pages or less.
Looking for references? We can help!
Since 1977, scientist around the world have used ALZET pumps to conduct their research, publishing their results in high-impact journals. The ALZET bibliography now contains over 16,000 publications! We can perform a custom search for references relevant to your research.
- Ensure around-the-clock exposure to test agents at predictable levels
- Permit continuous administration of short half-life proteins and peptides
- Provide a convenient method for the chronic dosing of laboratory animals
- Minimize unwanted experimental variables and ensure reproducible, consistent results
- Eliminate the need for nighttime or weekend dosing
- Reduce handling and stress to laboratory animals
- Small enough for use in mice or very young rats
- Allow for targeted delivery of agents to virtually any tissue
- Cost-effective research tool
What researchers are saying...
“...opioid and nonopioid analgesics were continuously infused from subcutaneously implanted osmotic mini-pumps, a convenient modality of drug delivery that allows for drug delivery at constant rate for prolonged periods of time without experimenter intervention.” Bruins Slot et al., Pharmacology, Biochemistry and Behavior 2002;72:943-951.