Links

ALZET Accessories

Animal diets (Research Diets Inc.): Custom Purified diets for laboratory animals

Braintree Scientific Inc.: Provides a variety of reseach equipment and supplies

Dental cement (Stoelting, Inc.)

Plastics One, Inc.: Wide selection of materials for brain cannulations (i.e. brain infusion cannulae, stabilizing screws, steel bits, pin vise)

ß-cyclodextrins: Alternative vehicle for enhancing the solubility of hydrophobic compounds.

ALZET International Distributors

Click here for a full list

ALZET Surgical Implantation Training & Resources

ALZET Surgical Implantation video (vimeo): This video describes surgical techniques for implantation of ALZET pumps in mice and rats. Demonstrated procedures include subcutaneous and intraperitoneal implantation, and the use of a catehter for intravenous (jugular), intrathecal, intragastric, and cerebral infusion.

NIH Guidelines for Survival Rodent Surgery

Principles of Rodent Surgery for the New Surgeon (JoVE video) (Link to PDF)

Direct intraventricular delivery of drugs to the rodent central nervous system. JoVE video article demonstrating ICV delivery to the mouse CNS using ALZET pumps.

Brain Infusion Kit implantation in mice (You Tube video by Vet Bio Institute)

Mouse external jugular catheterization and ALZET pump implantation: You Tube video by Univ. of Arizona College of Medicine

Animal models of Alzheimer's disease (including the Samaritan FAB rat): Taconic webinar on You Tube

Animal Research Resources

Institute for Laboratory Animal Research

American Association for Laboratory Animal Science (AALAS)

Cancer Models Database (caMOD)

Vet Technicians: Extensive digital library of learning resources for veterinary professionals

Contract Research Organizations/Laboratories

Charles River Labs

Jackson Labs

Augusta University (formerly Medical College of Georgia)

MPI Research

Product Safety Labs

reMYND

SRI International

Package Tracking

FedEx Package Tracking

UPS Package Tracking

Pharmaceutical Drug Delivery Technologies

DURECT Corporation

Reference books/articles

Pub Med Central: The U.S. National Library of Medicine's free digital archive of biomedical and life sciences journal literature.

Handbook of Pre-clinical Continuous Intravenous Infusion: Excellent overview of surgical procedures, equipment, and practical tips for conducting intravenous infusion studies in various laboratory animal species.

Scientific Societies

American Association for Cancer Research (AACR)

Federation for American Societies for Experimental Biology (FASEB)

International Union of Basic and Clinical Pharmacology (IUPHAR)

American Society of Gene Therapy (ASGT)

Society of Toxicology (SOT)

Society for Neuroscience (SFN)

The Endocrine Society (ENDO)

American Association for Laboratory Animal Science (AALAS)


Pump Advantages

  • Ensure around-the-clock exposure to test agents at predictable levels
  • Permit continuous administration of short half-life proteins and peptides
  • Provide a convenient method for the chronic dosing of laboratory animals
  • Minimize unwanted experimental variables and ensure reproducible, consistent results
  • Eliminate the need for nighttime or weekend dosing
  • Reduce handling and stress to laboratory animals
  • Small enough for use in mice or very young rats
  • Allow for targeted delivery of agents to virtually any tissue
  • Cost-effective research tool