These stainless steel devices facilitate stereotaxic placement of brain cannula onto the skull of laboratory animals for CNS delivery applications. They are specially designed to grip the removable tab on all ALZET brain infusion cannulae during brain cannulation. These cannula holders are compatible with most of the common stereotaxic frames available (i.e., Stoelting, Kopf, WPI, MyNeuroLab and Harvard Apparatus).
Cannula Holder 1
Order No. 0008860
- Designed to hold the removable cannula tab (3.4 mm diameter) on all ALZET brain infusion cannulae
- Features a narrow, non-intrusive cannula tip
Cannula Holder 2
Order No. 0008861
- Designed to hold the removable cannula tab (3.4 mm diameter) on all ALZET brain infusion cannulae
- Cannula positioned horizontally away from the stainless steel rod for easier visualization during cannulation
CSF Volume & Production Rate in Mice and rats
Mouse
- CSF Volume: 35 ul
- CSF Production Rate: 18 ul/hr
Rat
- CSF Volume: 150 ul
- CSF Production Rate: 180 ul/hr
Source: Pardridge, W.M., Transnasal and intraventricular delivery. In “Peptide Drug Delivery to the Brain” (Table 4.2) Raven Press, 1991:112.
