Animal models of human cardiovascular disease such as those for spontaneously hypertensive rats (SHR) or balloon injury have long represented an important area of research and discovery. Whether studying hypertension, restenosis, nitric oxide (NO) and NO synthase inhibitors, or the renin-angiotensin system, the use of ALZET osmotic pumps to deliver agents continuously provides a powerful tool for experimentation. ALZET pumps have been used to deliver antihypertensive drugs, angiogenic agents, compounds which inhibit vascular restenosis, and hormones with cardiovascular effects. The reference lists* shown below contain examples of these types of research.
*Some of these bibliographies have been truncated to keep the document to a reasonable length. These bibliographies are updated frequently. However, you can always contact us to request the most recent list of references, or additional references on your specific agent or research topic of interest.